Endocrine Abstracts

The central serotonin (5-hydroxytryptamine, 5-HT) system is an established modulator of energy balance. Therefore, it is unsurprising that former (e.g. D-fenfluramine), current (e.g. sibutramine), and drug discovery (e.g. lorcaserin) obesity treatments target serotonin pathways to affect food intake and body weight. Pharmacological and genetic research implicates the Gq-coupled serotonin 2C receptor (5-HT2CR) and the Gi-coupled serotonin 1B receptor (5-HT1BR) sp...

Background: Preexisting chronic autoimmune thyroiditis is the only known risk factor for thyroid lymphomas, a rare variant of thyroid cancer. Here, we describe a male patient with previously undiagnosed Hashimoto’s thyroiditis who presented with severe airway compromise due to a thyroid lymphoma.Case report: 60 y/o, former smoker, presented with 2 month neck fullness and dyspnea that awakened him throughout the night due to malpositioning of his nec...